Selected Incoming Publications

1. Muhammad Zubair, Tamzid Ibn Minhaj, Jun Wang, “Biomedical microsystems,” submitted

2. Jun Wang et al., “1,024-Channel Hybrid Voltage/Current-Clamp Neural Interface System-on-Chip with Dynamic Incremental-SAR for Acquisition and Intrinsic Spike Detection,” submitted

3. Jun Wang et al., “A 10,240-electrode and 4,096-channel CMOS chip with a switch matrix and DRAM-like current injectors for neuronal interfaces,” submitted

4. Jun Wang et al., “Long-term brain organoids electrophysiology monitoring with 3D CMOS nano-electrode array,” in preparation

5. Jun Wang et al., “4096-ch COMS-nano neural interface for multi-region in-vivo stimulation and recording,” in preparation

Published Research

1. Jun Wang*, Woo-Bin Jung*, Rona S. Gertner, Hongkun Park and Donhee Ham, “Synaptic connectivity mapping among thousands of neurons via parallelized intracellular recording with a microhole electrode array,” Nature Biomedical Engineering (2025). (PDF access: https://rdcu.be/ezgFH) 

2. Jun Wang*, Seok Joo Kim*, Wenxuan Wu*, Jongha Lee, Henry Hinton, Rona S. Gertner, Han Sae Jung, Hongkun Park, Donhee Ham, “A Cyto-silicon Hybrid System with On-chip Closed-loop Modulation,” IEEE Transactions on Biomedical Circuits and Systems (TBioCAS). (invited, early access DOI: 10.1109/TBCAS.2024.3466549)

3. Jun Wang, Ren Liu, Youngbin Tchoe, Alessio Paolo Buccino, Akshay Paul, Deborah Pre, Agnieszka D’Antonio-Chronowska, Frazer A Kelly, Anne G Bang, Chul Kim, Shadi Dayeh, Gert Cauwenberghs, “Low-Power Fully Integrated 256-Channel Nanowire Electrode-on-Chip Neural Interface for Intracellular Electrophysiology,” IEEE Transactions on Biomedical Circuits and Systems (TBioCAS). (invited, early access DOI: 10.1109/TBCAS.2024.3407794. )

4. Jun Wang*, Seok Joo Kim*, Wenxuan Wu*, Jongha Lee, Henry Hinton, Rona S. Gertner, Han Sae Jung, Hongkun Park, Donhee Ham, “A cyto-silicon hybrid system interfacing a CMOS electrode array with heart and brain cells with on-chip closed-loop modulation,” IEEE Biomedical Circuits and Systems Conference (BioCAS), 2023. (the best paper award, 1/170+)

5. Jun Wang, Akshay Paul, Dinghong Zhang, Jiajia Wu, Yuchen Xu, Yimin Zou, Chul Kim, Gert Cauwenberghs, “1,024-Electrode Hybrid Voltage/Current-Clamp Neural Interface System-on-Chip with Dynamic Incremental-SAR Acquisition,” IEEE Symposium on VLSI Circuits, 2020, pp. 1-2. (the 2nd best demo)

6. Jun Wang, Gert Cauwenberghs, Frederic D. Broccard, “Neuromorphic Dynamical Synapses with Reconfigurable Voltage-Gated Kinetics,” IEEE Transactions on Biomedical Engineering (TBME), vol. 67, no.7, pp. 1831-1840, July 2020.

7. J. Wang*, D. Breen*, A. Akinin, F. Broccard, H. D. I. Abarbanel and G. Cauwenberghs, “Assimilation of Biophysical Neuronal Dynamics in Neuromorphic VLSI,” IEEE Transactions on Biomedical Circuits and Systems (TBioCAS), vol. 11, no. 6, pp. 1258-1270, Dec. 2017. (invited)

8. DH Ren#, J Wang#, B Wang, Z You, “Probes for biomolecules detection based on RET-enhanced fluorescence polarization,” Biosensors and Bioelectronics 79, 802-809, 2016. (# Co-first author with advisor)

9. Y. -H. Hwang, J. Wang, D. -K. Jeong and J. -E. Park, “An Area/Power-Efficient ΔΣ Modulator Based on Dynamic-Boost Inverter for Multichannel Sensor Applications,” in IEEE Transactions on Very Large Scale Integration (VLSI) Systems, vol. 31, no. 9, pp. 1403-1412, Sept. 2023.

10. Woo-Bin Jung, Han Sae Jung, Jun Wang, Henry Hinton, Maxime Fournier, Adrian Horgan, Xavier Godron, Robert Nicol and Donhee Ham, “An aqueous analog MAC machine,” Advanced Materials 35, 2205096 (2023)

11. Han Sae Jung*, Woo-Bin Jung*, Jun Wang, Jeffrey Abbott, Adrian Horgan, Maxime Fournier, Henry Hinton, Young-Ha Hwang, Xavier Godron, Robert Nicol, Hongkun Park, and Donhee Ham, “CMOS electrochemical pH localizer-imager,” Science Advances 8, eabm6815 (2022)

12. A Paul, P Fowler, Y Xu, M Lee, J Wang, G Cauwenberghs, “Neural Recording Analog Front-End Noise Reduction with Digital Correlated Double Sampling”, IEEE Biomedical Circuits and Systems Conference (BioCAS), 149-152, 2022.

13. Jun Wang, Ren Liu, Youngbin Tchoe, Alessio Paolo Buccino, Akshay Paul, Agnieszka D'Antonio-Chronowska, Kelly A. Frazer, Kim Chul, Shadi Dayeh, Gert Cauwenberghs, “Low-Power 256-Channel Nanowire Electrode-on-Chip Neural Interface for Intracellular Electrophysiology,” IEEE Biomedical Circuits and Systems Conference (BioCAS), 2021.

14. Qingqing Yang, Qian Ma, Kate M. Herum, Chonghe Wang, Nirav Patel, Joon Lee, Shanshan Wang, Tony M. Yen, Jun Wang, Hanmei Tang, Yu-Hwa Lo, Brian P. Head, Farooq Azam, Sheng Xu, Gert Cauwenberghs, Andrew D. McCulloch, Scott John, Zhaowei Liu, Ratnesh Lal, “Array atomic force microscopy for real-time multiparametric analysis,” Proceedings of the National Academy of Sciences (PNAS). Mar 2019, 116 (13) 5872-5877.

15. C. Kim, S. Joshi, H. Courellis, J. Wang, C. Miller and G. Cauwenberghs, “Sub-uVrms-Noise Sub-uW/Channel ADC-Direct Neural Recording With 200-mV/ms Transient Recovery Through Predictive Digital Autoranging,” IEEE Journal of Solid-State Circuits (JSSC), vol. 53, no. 11, pp. 3101-3110, Nov. 2018.

16. C. Kim, S. Joshi, H. Courellis, J. Wang, C. Miller and G. Cauwenberghs, “A 92dB Dynamic Range Sub-μVrms Noise 0.8μW/ch Neural Recording ADC Array with Predictive Digital Autoranging,” International Solid-State Circuits Conference (ISSCC) 2018.

17. Frederic D Broccard, Siddharth Joshi, Jun Wang, Gert Cauwenberghs, “Neuromorphic neural interfaces: from neurophysiological inspiration to biohybrid coupling with nervous systems,” Journal of Neural Engineering (JNE), vol. 14, no. 4, pp. 041002, Jun. 2017.

18. J. Wang, T. Yu, A. Akinin, G. Cauwenberghs and F. D. Broccard, “Neuromorphic synapses with reconfigurable voltage-gated dynamics for biohybrid neural circuits,” IEEE Biomedical Circuits and Systems Conference (BioCAS), 2017, pp. 1-4.

19. J. Wang, D. Breen, A. Akinin, H. D. I. Abarbanel and G. Cauwenberghs, “Data Assimilation of Membrane Dynamics and Channel Kinetics with a Neuromorphic Integrated Circuit,” IEEE Biomedical Circuits and Systems Conference (BioCAS), 2016.

20. DH Ren#, J Wang#, Z You, “A Novel Probe for Multiplexed Detection of Intracellular Proteases based on FRET and Fluorescence Polarization,” Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015. (# Co-first author with advisor)

21. Dahai Ren#, Jun Wang#, Zheng You, “Long-term Monitoring of the Activity of Caspase-3 in Living Cells Based on FRET Probe Composed of QD, Nanogold and EGF,” RSC Adv. 4, 54907-54918, 2014. (# Co-first author with advisor)

22. Dahai Ren, Yiqiu Xia, Jun Wang, Zheng You. “Micropatterning of Single Cell Arrays Using PEG-Silane and Biotin-(Strept)Avidin System by Photolithography and Chemical Vapor Deposition,” Sensors and Actuators B: Chemical 188: 340-346, 2013.

23. D. H. Ren, M.Y. Cui, J. Wang, Z. You.Y.Y. Wang, “A Single Cells Patterning Approach for Human Promyelocytic Leukemia Cells,” Key Engineering Materials, Vols. 562-565, pp. 1273-1278, 2013.

24. J Wang, XL Zhang, J Yuan, XF Shi, XM, Gao, “Development of Universal Multi-function Digital Remote Control Electronic Switch Based on WSN,” Key Engineering Materials. 464: 142-145, 2011.

Book Chapters

1. Abraham Akinin, Akshay Paul, Jun Wang, Alessio P. Buccino, Gert Cauwenberghs, “Chapter 2: Biopotential Measurements and Electrodes” in Neural Engineering, Springer.

2. Broccard, FD, Joshi, S., Wang, J. and Cauwenberghs, G., “Neuromorphic neural interfaces” in Neuroengineering Handbook, Edited by Nitish V. Thakor, Springer.

Patents

1. Jun Wang, Gert Cauwenberghs, “Dynamic Incremental-SAR Analog-to-Digital Conversion,” US Patent App. 18/001,686 (Licensed by NextSense Inc.)

2. Donhee Ham, Jun Wang, Nadir Talha, “A method of extracting synaptic connection strength,” H0498.70846US00

3. Donhee Ham, Jun Wang, Woo-Bin Jung, Hongkun Park, “Systems and Methods for High-Density Long-Term Intracellular Electrophysiology,” PCT/US2023/016198

4. Donhee Ham, Jun Wang, Yuchang Zhang, Hongkun Park, “Reconfigurable Multi-electrode Apparatus,” 63/482,262

5. Donhee Ham, Jun Wang, Yuchang Zhang, Hongkun Park, “Dram-style Bidirectional Current Injector and Multi-electrode Apparatus with Dram-style Bidirectional Current Injectors,” 63/482,269

6. Donhee Ham, Seokjoo Kim, Haju Kim, Jun Wang, “Memristor Mapping of Biological Neuronal Connectivity,” 63/588,656

7. Donhee Ham, Woo-Bin Jung, Han Sae Jung, Jun Wang, Youngha Hwang, Henry Julian Hinton, Jeffrey T. Abbott and Hongkun Park, “Local Sensing and Control of PH for Parallelized Synthesis,” US Patent App. 18/569,809

8. Akshay Paul, Preston Fowler, XU Yuchen, Jun Wang, Gert Cauwenberghs, “Dynamic incremental analog-to-digital conversion interfaces for in-ear electrophysiology,” US Patent App. 18/570,534, 2024

9. Hongkun Park, Donhee Ham, Kevin M. Cheung, Licheng Wang, Jun Wang, Anna Blanchfield, Rona Gertner, and Xuechun Wang, “Devices and Methods for Multiplexed Chemical and Electrical Measurements of Neurons Using CMOS Electrode Arrays,” No. 63/706,611

10. 4 Patents in China. 2010- 2014 (First author in students)